【进展|热点】CELL：抗病毒天然免疫取得新进展
丁香园论坛
865
北大生命科学院今日发表在cell上的一篇文章称：病毒或胞质内的核酸可通过sting募集stat6至内质网，从而使得stat6磷酸化而被激活，转移至核内诱导免疫细胞归巢相关特异性基因的表达。
Cell. 2011 Oct 14;147(2):436-46.
Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity.
Chen H, Sun H, You F, Sun W, Zhou X, Chen L, Yang J, Wang Y, Tang H, Guan Y, Xia W, Gu J, Ishikawa H, Gutman D, Barber G, Qin Z, Jiang Z.
Source
State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China; Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, School of Life Sciences, Peking University, Beijing, China.
全文见附件
Cell. 2011 Oct 14;147(2):436-46.
Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity.
Chen H, Sun H, You F, Sun W, Zhou X, Chen L, Yang J, Wang Y, Tang H, Guan Y, Xia W, Gu J, Ishikawa H, Gutman D, Barber G, Qin Z, Jiang Z.
Source
State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China; Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, School of Life Sciences, Peking University, Beijing, China.
全文见附件
