Oxygen Consumption Methods: Xanthine Oxidase and Lipoxygenase
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A biochemical paradox that has been observed for many years is now becoming understood: O2 , essential for the aerobic life forms, can be inappropriately metabolized, becoming toxic to an organism. Mammals derive most of their cellular adenosine triphosphate (ATP) from the controlled four-electron reduction of O2 , to form H2 O by the mitochondrial electron-transport system. Approximately 98% of all O2 consumed by cells enters the mitochondria, where it is reduced by a terminal oxidase, such as cytochrome oxidase.
