Software for Genetic Linkage Analysis: An Update
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Reviews describing the software available to support genetic linkage analysis have appeared intermittently over the last few years (1 ,1a ). This period has been associated with several significant influences that have made it timely to reconsider the available programs and related computing resources. These influences are:
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The growth of the Internet;
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The adoption of Unix as the most common platform for software development;
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The appearance of genome centers that offer database and analytical resources; and
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Theoretical and technical advances in the development of algorithms for mapping general genetic traits (2 –4 ), constructing dense genetic maps of whole chromosomes (5 ), and for conducting genome-wide screening projects for common diseases such as diabetes (6 ).
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