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Special Issue: Liver Proteomics – Also the 2010 Journal of Proteome Research Sample Issue
Please take a moment to browse through this free sample issue to investigate the broad coverage of the field available in a given issue of the Journal of Proteome Research. This issue is also a Special Issue, with a portion of the research highlighting advances in liver proteomics. Also experience, first-hand, the ACS Publications Award-Winning Web Editions Platform, providing a state-of-the-art online experience for information discovery, interactivity, and research productivity for JPR readers.
“Beside the fact that the liver is the largest organ in the body, probably second only to the brain in organ complexity, the strongest and most compelling argument for a proteome initiative that focuses on the liver is the essential and multi-function role of the liver in human health and disease.” Read More
~Guest Editor: Laura M. Beretta, Fred Hutchinson Cancer Research Center
“As an important part of the output from CNHLPP, this special issue contains articles that address a part of the research findings from its pilot phase, mainly on the Expression Profiling with its data mining. These papers describe the standard operation procedures of the sample collection and pretreatment, proteomic technology strategy, expression profiling, data sets infrastructure, data integration and annotation, and many associated studies.” Read More
~Guest Editors: Fuchu He, Beijing Institute of Radiation Medicine, Maxey C. M. Chung, National University of Singapore and T. William Jordan, Victoria University of Wellington
Journal of Proteome Research, Volume 9, Issue 1 – Sample Issue
The Liver Proteome Editorial
Chinese Human Liver Proteome Project: A Pathfinder of HUPO Human Liver Proteome Project
Fuchu He, Maxey C. M. Chung, T. William Jordan
DOI: 10.1021/pr900742f
nHUPO’s Effort To Define the Liver Proteome
Laura Beretta
DOI: 10.1021/pr100011s
Research Profile
Mammoth data set from human liver reported
Quinn Martin Eastman
DOI: 10.1021/pr9007464
A new PTM for tubulin is found in a parasite
Katie Cottingham
DOI: 10.1021/pr901030w
Research Articles
Cell Characterization by Proteome Profiling Applied to Primary Hepatocytes and Hepatocyte Cell Lines Hep-G2 and Hep-3B
Astrid Slany, Verena J. Haudek, Hannes Zwickl, Nina C. Gundacker, Michael Grusch, Thomas S. Weiss, Katja Seir, Chantal Rodgarkia-Dara, Claus Hellerbrand and Christopher Gerner
DOI: 10.1021/pr900057t
A Proteomics Analysis of Rat Liver Membrane Skeletons: The Investigation of Actin- and Cytokeratin-Based Protein Components
Qingsong Wang, Jintang He, Lingyao Meng, Yashu Liu, Hai Pu and Jianguo Ji
DOI: 10.1021/pr900102n
Novel Autoimmune Hepatitis-Specific Autoantigens Identified Using Protein Microarray Technology
Qifeng Song, Guozhen Liu, Shaohui Hu, Yan Zhang, Yong Tao, Yuning Han, Haipan Zeng, Wei Huang, Fang Li, Peng Chen, Jianhui Zhu, Chaojun Hu, Shulan Zhang, Yongzhe Li, Heng Zhu and Lin Wu
DOI: 10.1021/pr900131e
The Role of Translationally Controlled Tumor Protein in Tumor Growth and Metastasis of Colon Adenocarcinoma Cells
Qiang Ma, Yan Geng, Weiwen Xu, Yingsong Wu, Fuli He, Wen Shu, Maoliang Huang, Hongyan Du and Ming Li
DOI: 10.1021/pr9001367
Liverbase: A Comprehensive View of Human Liver Biology
Aihua Sun, Ying Jiang, Xue Wang, Qijun Liu, Fan Zhong, Quanyuan He, Wei Guan, Hao Li, Yulin Sun, Liang Shi, Hong Yu, Dong Yang, Yang Xu, Yanping Song, Wei Tong, Dong Li, Chengzhao Lin, Yunwei Hao, Chao Geng, Dong Yun, Xuequn Zhang, Xiaoyan Yuan, Ping Chen, Yunping Zhu, Yixue Li, Songping Liang, Xiaohang Zhao, Siqi Liu and Fuchu He
DOI: 10.1021/pr900191p
NMR-Based Metabolic Profiling Identifies Biomarkers of Liver Regeneration Following Partial Hepatectomy in the Rat
Mary E. Bollard, Nancy R. Contel, Timothy M. D. Ebbels, Leon Smith, Olaf Beckonert, Glenn H. Cantor, Lois Lehman-McKeeman, Elaine C. Holmes, John C. Lindon, Jeremy K. Nicholson and Hector C. Keun
DOI: 10.1021/pr900200v
Circulating Lamin B1 (LMNB1) Biomarker Detects Early Stages of Liver Cancer in Patients
Stella Sun, Michelle Z. Xu, Ronnie T. Poon, Philip J. Day and John M. Luk
DOI: 10.1021/pr9002118
First Insight into the Human Liver Proteome from PROTEOMESKY-LIVERHu 1.0, a Publicly Available Database
DOI: 10.1021/pr900532r
Application of Slicing of One-Dimensional Gels with Subsequent Slice-by-Slice Mass Spectrometry for the Proteomic Profiling of Human Liver Cytochromes P450
Andrey V. Lisitsa, Natalia A. Petushkova, Herbert Thiele, Sergei A. Moshkovskii, Viktor G. Zgoda, Irina I. Karuzina, Aleksey L. Chernobrovkin, Oleg G. Skipenko and Alexander I. Archakov
DOI: 10.1021/pr900262z
Identification of N-Glycan Serum Markers Associated with Hepatocellular Carcinoma from Mass Spectrometry Data
Zhiqun Tang, Rency S. Varghese, Slavka Bekesova, Christopher A. Loffredo, Mohamed Abdul Hamid, Zuzana Kyselova, Yehia Mechref, Milos V. Novotny, Radoslav Goldman and Habtom W. Ressom
DOI: 10.1021/pr900397n
Peroxisomes from the Heavy Mitochondrial Fraction: Isolation by Zonal Free Flow Electrophoresis and Quantitative Mass Spectrometrical Characterization
Markus Islinger, Ka Wan Li, Maarten Loos, Sven Liebler, Sabine Angermüller, Christoph Eckerskorn, Gerhard Weber, Afsaneh Abdolzade and Alfred Völkl
DOI: 10.1021/pr9004663
Technical Notes
Metabonomic Evaluation of Melamine-Induced Acute Renal Toxicity in Rats
Guoxiang Xie, Xiaojiao Zheng, Xin Qi, Yu Cao, Yi Chi, Mingming Su, Yan Ni, Yunping Qiu, Yumin Liu, Houkai Li, Aihua Zhao and Wei Jia
DOI: 10.1021/pr900333h
An Altered Pattern of Liver Apolipoprotein A-I Isoforms Is Implicated in Male Chronic Hepatitis B Progression
Fu Yang, Yixuan Yin, Fang Wang, Ling Zhang, Yuqi Wang and Shuhan Sun
DOI: 10.1021/pr900593r
Review
The Red Blood Cell Proteome and Interactome: An Update
Angelo D’Alessandro, Pier Giorgio Righetti and Lello Zolla
DOI: 10.1021/pr900831f
Research Articles
Serum and Tissue Profiling in Bladder Cancer Combining Protein and Tissue Arrays
Esteban Orenes-Piñero, Rodrigo Barderas, Daniel Rico, J. Ignacio Casal, David Gonzalez-Pisano, Jose Navajo, Ferran Algaba, Josep Maria Piulats and Marta Sanchez-Carbayo
DOI: 10.1021/pr900273u
Characterization of the Phosphoproteome in LNCaP Prostate Cancer Cells by In-Gel Isoelectric Focusing and Tandem Mass Spectrometry
Li Chen, Francesco Giorgianni and Sarka Beranova-Giorgianni
DOI: 10.1021/pr900338q
Different Changes in Protein and Phosphoprotein Levels Result from Serum Starvation of High-Grade Glioma and Adenocarcinoma Cell Lines
Victor A. Levin, Sonali C. Panchabhai, Li Shen, Steven M. Kornblau, Yihua Qiu and Keith A. Baggerly
DOI: 10.1021/pr900392b
Oligomeric Characterization of the Photosynthetic Apparatus of Rhodobacter sphaeroides R26.1 by Nondenaturing Electrophoresis Methods
Gian Maria D’Amici, Sara Rinalducci, Leonardo Murgiano, Francesca Italiano and Lello Zolla
DOI: 10.1021/pr9005052
Integrated Proteomic Analysis Reveals a Substantial Enrichment of Protein Trafficking Processes in Hippocampus Tissue after Hypoxic Stress
Roos Van Elzen, Bart Ghesquière, Evy Timmerman, Stefaan Vandamme, Luc Moens, Kris Gevaert and Sylvia Dewilde
DOI: 10.1021/pr900517m
Profiling Protein Markers Associated with Lymph Node Metastasis in Prostate Cancer by DIGE-based Proteomics Analysis
Jun Pang, Wei-Peng Liu, Xiao-Peng Liu, Liao-Yuan Li, You-Qiang Fang, Qi-Peng Sun, Shao-Jun Liu, Ming-Tao Li, Zu-Lan Su and Xin Gao
DOI: 10.1021/pr900953s
Tandem 18O Stable Isotope Labeling for Quantification of N-Glycoproteome
Ze Liu, Jing Cao, Yifeng He, Liang Qiao, Congjian Xu, Haojie Lu and Pengyuan Yang
DOI: 10.1021/pr900528j
Differential Proteomic Profiling Identifies Novel Molecular Targets of Paclitaxel and Phytoagent Deoxyelephantopin against Mammary Adenocarcinoma Cells
Wai-Leng Lee, Tuan-Nan Wen, Jeng-Yuan Shiau and Lie-Fen Shyur
DOI: 10.1021/pr900543e
Functional Divergence of Helicobacter pylori Related to Early Gastric Cancer
Kuvat T. Momynaliev, Sergey V. Kashin, Vera V. Chelysheva, Oksana V. Selezneva, Irina A. Demina, Marya V. Serebryakova, Dmitry Alexeev, Vladimir A. Ivanisenko, Ewgeniya Aman and Vadim M. Govorun
DOI: 10.1021/pr900586w
Proteomic Analyses of the Developing Chicken Cardiovascular System
Els Bon, Regine Steegers, Eric A. P. Steegers, Nicolette Ursem, Halima Charif, Peter C. Burgers, Theo M. Luider and Lennard J. M. Dekker
DOI: 10.1021/pr900614w
Phosphoproteomic Analysis Reveals the Multiple Roles of Phosphorylation in Pathogenic Bacterium Streptococcus pneumoniae
Xuesong Sun, Feng Ge, Chuan-Le Xiao, Xing-Feng Yin, Ruiguang Ge, Liu-Hui Zhang and Qing-Yu He
DOI: 10.1021/pr900612v
Temporal Proteomics Profiling of Lipid Rafts in CCR6-Activated T Cells Reveals the Integration of Actin Cytoskeleton Dynamics
Shu-Ling Lin, Chih-Wei Chien, Chia-Li Han, Eric S.-W. Chen, Shao-Hsuan Kao, Yu-Ju Chen and Fang Liao
DOI: 10.1021/pr9006156
Ambient pH Stress Inhibits Spore Germination of Penicillium expansum by Impairing Protein Synthesis and Folding: A Proteomic-Based Study
Boqiang Li, Tongfei Lai, Guozheng Qin and Shiping Tian
DOI: 10.1021/pr900622j
Simple Method for Quantitative Analysis of N-Linked Glycoproteins in Hepatocellular Carcinoma Specimens
Hyoung-Joo Lee, Keun Na, Eun-Young Choi, Kyung Sik Kim, Hoguen Kim and Young-Ki Paik
DOI: 10.1021/pr900649b
Metabolic Profiling of Human Lung Cancer Tissue by 1H High Resolution Magic Angle Spinning (HRMAS) NMR Spectroscopy
Cáludia M. Rocha, António S. Barros, Ana M. Gil, Brian J. Goodfellow, Eberhard Humpfer, Manfred Spraul, Isabel M. Carreira, Joana B. Melo, João Bernardo, Ana Gomes, Vitor Sousa, Lina Carvalho and Iola F. Duarte
DOI: 10.1021/pr9006574
Development of High-Throughput Chemical Extraction Techniques and Quantitative HPLC-MS/MS (SRM) Assays for Clinically Relevant Plasma Proteins
Chris Barton, Richard G. Kay, Wolfgang Gentzer, Frank Vitzthum and Steve Pleasance
DOI: 10.1021/pr900658d
Worms from Venus and Mars: Proteomics Profiling of Sexual Differences in Caenorhabditis elegans Using in Vivo 15N Isotope Labeling
Bastiaan B. J. Tops, Sharon Gauci, Albert J. R. Heck and Jeroen Krijgsveld
DOI: 10.1021/pr900678j
Quantitative Plasma Proteomic Profiling Identifies the Vitamin E Binding Protein Afamin as a Potential Pathogenic Factor in SIV Induced CNS Disease
Gurudutt Pendyala, Sunia A. Trauger, Gary Siuzdak and Howard S. Fox
DOI: 10.1021/pr900685u
Post-Translational Modifications to Toxoplasma gondii α- and β-Tubulins Include Novel C-Terminal Methylation
Hui Xiao, Kamal El Bissati, Pascal Verdier-Pinard, Berta Burd, Hongshan Zhang, Kami Kim, Andras Fiser, Ruth Hogue Angeletti and Louis M. Weiss
DOI: 10.1021/pr900699a
Global Genomic and Proteomic Analysis Identifies Biological Pathways Related to High-Risk Neuroblastoma
Qing-Rong Chen, Young K. Song, Li-Rong Yu, Jun S. Wei, Joon-Yong Chung, Stephen M. Hewitt, Timothy D. Veenstra and Javed Khan
DOI: 10.1021/pr900701v
Detecting Changes in the Thiol Redox State of Proteins Following a Decrease in Oxygen Concentration Using a Dual Labeling Technique
James K. C. Lui, Richard Lipscombe and Peter G. Arthur
DOI: 10.1021/pr900702z
MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics
Peter Mortensen, Joost W. Gouw, Jesper V. Olsen, Shao-En Ong, Kristoffer T. G. Rigbolt, Jakob Bunkenborg, Jürgen Cox, Leonard J. Foster, Albert J. R. Heck, Blagoy Blagoev, Jens S. Andersen and Matthias Mann
DOI: 10.1021/pr900721e
Probing the Metabolic Aberrations Underlying Mutant Huntingtin Toxicity in Yeast and Assessing Their Degree of Preservation in Humans and Mice
P. Matthew Joyner, Ronni M. Matheke, Lindsey M. Smith and Robert H. Cichewicz
DOI: 10.1021/pr900734g
Effect of the Histone Deacetylase Inhibitor Trichostatin A on the Metabolome of Cultured Primary Hepatocytes
James K. Ellis, Pui Hei Chan, Tatyana Doktorova, Toby J. Athersuch, Rachel Cavill, Tamara Vanhaecke, Vera Rogiers, Mathieu Vinken, Jeremy K. Nicholson, Timothy M. D. Ebbels and Hector C. Keun
DOI: 10.1021/pr9007656
Ceramide Kinase Profiling by Mass Spectrometry Reveals a Conserved Phosphorylation Pattern Downstream of the Catalytic Site
Wei-Qiang Chen, Christine Graf, David Zimmel, Philipp Rovina, Kurt Krapfenbauer, Markus Jaritz, Peter J. Parker, Gert Lubec and Frédéric Bornancin
DOI: 10.1021/pr900763z
Quantitative Phosphoproteomic Analysis of the STAT3/IL-6/HIF1α Signaling Network: An Initial Study in GSC11 Glioblastoma Stem Cells
Carol L. Nilsson, Roslyn Dillon, Arugadoss Devakumar, Stone D.-H. Shi, Michael Greig, John C. Rogers, Bryan Krastins, Michael Rosenblatt, Gregory Kilmer, Michael Major, Barbara J. Kaboord, David Sarracino, Taha Rezai, Amol Prakash, Mary Lopez, Yongjie Ji, Waldemar Priebe, Frederick F. Lang, Howard Colman and Charles A. Conrad
DOI: 10.1021/pr9007927
Acetone Precipitation of Proteins and the Modification of Peptides
Deborah M. Simpson and Robert J. Beynon
DOI: 10.1021/pr900806x
Proteomic Identification of Overexpressed PRDX 1 and Its Clinical Implications in Ovarian Carcinoma
Kwang-hoe Chung, Dong Hyeon Lee, Youkyong Kim, Tae-heon Kim, Jin Hyong Huh, Sang-geun Chung, Sunyoung Lee, Chan Lee, Jung Jae Ko and Hee Jung An
DOI: 10.1021/pr900811x
Hyperglycemia Alters the Schwann Cell Mitochondrial Proteome and Decreases Coupled Respiration in the Absence of Superoxide Production
Liang Zhang, Cuijuan Yu, Francisco E. Vasquez, Nadya Galeva, Isaac Onyango, Russell H. Swerdlow and Rick T. Dobrowsky
DOI: 10.1021/pr900818g
Phenotyping of an in Vitro Model of Ischemic Penumbra by iTRAQ-Based Shotgun Quantitative Proteomics
Arnab Datta, Jung Eun Park, Xin Li, Huoming Zhang, Zhi Shan Ho, Klaus Heese, Sai Kiang Lim, James P. Tam and Siu Kwan Sze
DOI: 10.1021/pr900829h
Comparative Protein Profiling Reveals Minichromosome Maintenance (MCM) Proteins As Novel Potential Tumor Markers for Meningiomas
Okay Saydam, Ozlem Senol, Tieneke B. M. Schaaij-Visser, Thang V. Pham, Sander R. Piersma, Anat O. Stemmer-Rachamimov, Thomas Wurdinger, Saskia M. Peerdeman and Connie R. Jimenez
DOI: 10.1021/pr900834h
Quantitative Organelle Proteomics of MCF-7 Breast Cancer Cells Reveals Multiple Subcellular Locations for Proteins in Cellular Functional Processes
Amal T. Qattan, Claire Mulvey, Mark Crawford, Darren A. Natale and Jasminka Godovac-Zimmermann
DOI: 10.1021/pr9008332
Proteomic Analysis of the Murine Liver in Response to a Combined Exposure to Psychological Stress and 7,12-Dimethylbenz(a)anthracene
Melanie S. Flint, Brian L. Hood, Mai Sun, Nicolas A. Stewart, Jacqueline Jones-Laughner and Thomas P. Conrads
DOI: 10.1021/pr900861j
Expression Profiling of Fibroblasts Identifies Cell Cycle Abnormalities in Schizophrenia
L. Wang, H. E. Lockstone, P. C. Guest, Y. Levin, A. Palotás, S. Pietsch, E. Schwarz, H. Rahmoune, L. W. Harris, D. Ma and S. Bahn
DOI: 10.1021/pr900867x
Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America
Juan J. Calvete, Libia Sanz, Pedro Cid, Pilar de la Torre, Marietta Flores-Díaz, M. Cristina Dos Santos, Adolfo Borges, Adolfo Bremo, Yamileth Angulo, Bruno Lomonte, Alberto Alape-Girón and José María Gutiérrez
DOI: 10.1021/pr9008749
Identification of Serum Biomarkers for Colorectal Cancer Metastasis Using a Differential Secretome Approach
Hua Xue, Bingjian Lü, Jun Zhang, Minliang Wu, Qiong Huang, Qiang Wu, Hongqiang Sheng, Dongdong Wu, Jianwen Hu and Maode Lai
DOI: 10.1021/pr9008817
The SMN Interactome Includes Myb-Binding Protein 1a
Heidi R. Fuller, Nguyen Thi Man, Le Thanh Lam, Le Thiet Thanh, Rebecca A. Keough, Arndt Asperger, Thomas J. Gonda and Glenn E. Morris
DOI: 10.1021/pr900884g
Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches
José María Gutiérrez, Libia Sanz, Marietta Flores-Díaz, Lucía Figueroa, Marvin Madrigal, María Herrera, Mauren Villalta, Guillermo León, Ricardo Estrada, Adolfo Borges, Alberto Alape-Girón and Juan J. Calvete
DOI: 10.1021/pr9009518
Technical Notes
The Effects of Rosiglitazone and High Glucose on Protein Expression in Endothelial Cells
Renato Millioni, Lucia Puricelli, Elisabetta Iori, Giorgio Arrigoni and Paolo Tessari
DOI: 10.1021/pr900435z
MS/MS/MS Reveals False Positive Identification of Histone Serine Methylation
Junmei Zhang, Yue Chen, Zhihong Zhang, Gang Xing, Joanna Wysocka and Yingming Zhao
DOI: 10.1021/pr900864s
Evaluating the Performance of New Approaches to Spot Quantification and Differential Expression in 2-Dimensional Gel Electrophoresis Studies
Jeffrey S. Morris, Brittan N. Clark, Wei Wei and Howard B. Gutstein
DOI: 10.1021/pr9005603
Artificial Decoy Spectral Libraries for False Discovery Rate Estimation in Spectral Library Searching in Proteomics
Henry Lam, Eric W. Deutsch and Ruedi Aebersold
DOI: 10.1021/pr900947u
Identification of Neisseria meningitidis Outer Membrane Vesicle Complexes Using 2-D High Resolution Clear Native/SDS-PAGE
Juan Marzoa, Sandra Sánchez, Carlos M. Ferreirós and María Teresa Criado
DOI: 10.1021/pr9006409
MRMaid-DB: A Repository of Published SRM Transitions
Jennifer A. Cham (Mead), Luca Bianco, Chris Barton and Conrad Bessant
DOI: 10.1021/pr900713u
New Algorithm for the Identification of Intact Disulfide Linkages Based on Fragmentation Characteristics in Tandem Mass Spectra
Seonhwa Choi, Jaeho Jeong, Seungjin Na, Hyo Sun Lee, Hwa-Young Kim, Kong-Joo Lee and Eunok Paek
DOI: 10.1021/pr900771r
The Journal of Proteome Research provides content encompassing all aspects of global protein analysis and function, emphasizing the synergy between physical and life sciences resulting in a multidisciplinary approach to the understanding of biological processes.
In 2008 the Journal of Proteome Research recorded an ISI Impact Factor of 5.684 and 39% growth in total citations to 8,043 as reported in the 2008 Journal Citations Reports® by Thomson Reuters.
Already have access to the Journal of Proteome Research through your company or institution? Check out sample issues from all ACS titles and expand your knowledge base. Here are a few titles that may be of special interest to you:
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Special Issue: Liver Proteomics – Also the 2010 Journal of Proteome Research Sample Issue
Please take a moment to browse through this free sample issue to investigate the broad coverage of the field available in a given issue of the Journal of Proteome Research. This issue is also a Special Issue, with a portion of the research highlighting advances in liver proteomics. Also experience, first-hand, the ACS Publications Award-Winning Web Editions Platform, providing a state-of-the-art online experience for information discovery, interactivity, and research productivity for JPR readers.
“Beside the fact that the liver is the largest organ in the body, probably second only to the brain in organ complexity, the strongest and most compelling argument for a proteome initiative that focuses on the liver is the essential and multi-function role of the liver in human health and disease.” Read More
~Guest Editor: Laura M. Beretta, Fred Hutchinson Cancer Research Center
“As an important part of the output from CNHLPP, this special issue contains articles that address a part of the research findings from its pilot phase, mainly on the Expression Profiling with its data mining. These papers describe the standard operation procedures of the sample collection and pretreatment, proteomic technology strategy, expression profiling, data sets infrastructure, data integration and annotation, and many associated studies.” Read More
~Guest Editors: Fuchu He, Beijing Institute of Radiation Medicine, Maxey C. M. Chung, National University of Singapore and T. William Jordan, Victoria University of Wellington
Journal of Proteome Research, Volume 9, Issue 1 – Sample Issue
The Liver Proteome Editorial
Chinese Human Liver Proteome Project: A Pathfinder of HUPO Human Liver Proteome Project
Fuchu He, Maxey C. M. Chung, T. William Jordan
DOI: 10.1021/pr900742f
nHUPO’s Effort To Define the Liver Proteome
Laura Beretta
DOI: 10.1021/pr100011s
Research Profile
Mammoth data set from human liver reported
Quinn Martin Eastman
DOI: 10.1021/pr9007464
A new PTM for tubulin is found in a parasite
Katie Cottingham
DOI: 10.1021/pr901030w
Research Articles
Cell Characterization by Proteome Profiling Applied to Primary Hepatocytes and Hepatocyte Cell Lines Hep-G2 and Hep-3B
Astrid Slany, Verena J. Haudek, Hannes Zwickl, Nina C. Gundacker, Michael Grusch, Thomas S. Weiss, Katja Seir, Chantal Rodgarkia-Dara, Claus Hellerbrand and Christopher Gerner
DOI: 10.1021/pr900057t
A Proteomics Analysis of Rat Liver Membrane Skeletons: The Investigation of Actin- and Cytokeratin-Based Protein Components
Qingsong Wang, Jintang He, Lingyao Meng, Yashu Liu, Hai Pu and Jianguo Ji
DOI: 10.1021/pr900102n
Novel Autoimmune Hepatitis-Specific Autoantigens Identified Using Protein Microarray Technology
Qifeng Song, Guozhen Liu, Shaohui Hu, Yan Zhang, Yong Tao, Yuning Han, Haipan Zeng, Wei Huang, Fang Li, Peng Chen, Jianhui Zhu, Chaojun Hu, Shulan Zhang, Yongzhe Li, Heng Zhu and Lin Wu
DOI: 10.1021/pr900131e
The Role of Translationally Controlled Tumor Protein in Tumor Growth and Metastasis of Colon Adenocarcinoma Cells
Qiang Ma, Yan Geng, Weiwen Xu, Yingsong Wu, Fuli He, Wen Shu, Maoliang Huang, Hongyan Du and Ming Li
DOI: 10.1021/pr9001367
Liverbase: A Comprehensive View of Human Liver Biology
Aihua Sun, Ying Jiang, Xue Wang, Qijun Liu, Fan Zhong, Quanyuan He, Wei Guan, Hao Li, Yulin Sun, Liang Shi, Hong Yu, Dong Yang, Yang Xu, Yanping Song, Wei Tong, Dong Li, Chengzhao Lin, Yunwei Hao, Chao Geng, Dong Yun, Xuequn Zhang, Xiaoyan Yuan, Ping Chen, Yunping Zhu, Yixue Li, Songping Liang, Xiaohang Zhao, Siqi Liu and Fuchu He
DOI: 10.1021/pr900191p
NMR-Based Metabolic Profiling Identifies Biomarkers of Liver Regeneration Following Partial Hepatectomy in the Rat
Mary E. Bollard, Nancy R. Contel, Timothy M. D. Ebbels, Leon Smith, Olaf Beckonert, Glenn H. Cantor, Lois Lehman-McKeeman, Elaine C. Holmes, John C. Lindon, Jeremy K. Nicholson and Hector C. Keun
DOI: 10.1021/pr900200v
Circulating Lamin B1 (LMNB1) Biomarker Detects Early Stages of Liver Cancer in Patients
Stella Sun, Michelle Z. Xu, Ronnie T. Poon, Philip J. Day and John M. Luk
DOI: 10.1021/pr9002118
First Insight into the Human Liver Proteome from PROTEOMESKY-LIVERHu 1.0, a Publicly Available Database
DOI: 10.1021/pr900532r
Application of Slicing of One-Dimensional Gels with Subsequent Slice-by-Slice Mass Spectrometry for the Proteomic Profiling of Human Liver Cytochromes P450
Andrey V. Lisitsa, Natalia A. Petushkova, Herbert Thiele, Sergei A. Moshkovskii, Viktor G. Zgoda, Irina I. Karuzina, Aleksey L. Chernobrovkin, Oleg G. Skipenko and Alexander I. Archakov
DOI: 10.1021/pr900262z
Identification of N-Glycan Serum Markers Associated with Hepatocellular Carcinoma from Mass Spectrometry Data
Zhiqun Tang, Rency S. Varghese, Slavka Bekesova, Christopher A. Loffredo, Mohamed Abdul Hamid, Zuzana Kyselova, Yehia Mechref, Milos V. Novotny, Radoslav Goldman and Habtom W. Ressom
DOI: 10.1021/pr900397n
Peroxisomes from the Heavy Mitochondrial Fraction: Isolation by Zonal Free Flow Electrophoresis and Quantitative Mass Spectrometrical Characterization
Markus Islinger, Ka Wan Li, Maarten Loos, Sven Liebler, Sabine Angermüller, Christoph Eckerskorn, Gerhard Weber, Afsaneh Abdolzade and Alfred Völkl
DOI: 10.1021/pr9004663
Technical Notes
Metabonomic Evaluation of Melamine-Induced Acute Renal Toxicity in Rats
Guoxiang Xie, Xiaojiao Zheng, Xin Qi, Yu Cao, Yi Chi, Mingming Su, Yan Ni, Yunping Qiu, Yumin Liu, Houkai Li, Aihua Zhao and Wei Jia
DOI: 10.1021/pr900333h
An Altered Pattern of Liver Apolipoprotein A-I Isoforms Is Implicated in Male Chronic Hepatitis B Progression
Fu Yang, Yixuan Yin, Fang Wang, Ling Zhang, Yuqi Wang and Shuhan Sun
DOI: 10.1021/pr900593r
Review
The Red Blood Cell Proteome and Interactome: An Update
Angelo D’Alessandro, Pier Giorgio Righetti and Lello Zolla
DOI: 10.1021/pr900831f
Research Articles
Serum and Tissue Profiling in Bladder Cancer Combining Protein and Tissue Arrays
Esteban Orenes-Piñero, Rodrigo Barderas, Daniel Rico, J. Ignacio Casal, David Gonzalez-Pisano, Jose Navajo, Ferran Algaba, Josep Maria Piulats and Marta Sanchez-Carbayo
DOI: 10.1021/pr900273u
Characterization of the Phosphoproteome in LNCaP Prostate Cancer Cells by In-Gel Isoelectric Focusing and Tandem Mass Spectrometry
Li Chen, Francesco Giorgianni and Sarka Beranova-Giorgianni
DOI: 10.1021/pr900338q
Different Changes in Protein and Phosphoprotein Levels Result from Serum Starvation of High-Grade Glioma and Adenocarcinoma Cell Lines
Victor A. Levin, Sonali C. Panchabhai, Li Shen, Steven M. Kornblau, Yihua Qiu and Keith A. Baggerly
DOI: 10.1021/pr900392b
Oligomeric Characterization of the Photosynthetic Apparatus of Rhodobacter sphaeroides R26.1 by Nondenaturing Electrophoresis Methods
Gian Maria D’Amici, Sara Rinalducci, Leonardo Murgiano, Francesca Italiano and Lello Zolla
DOI: 10.1021/pr9005052
Integrated Proteomic Analysis Reveals a Substantial Enrichment of Protein Trafficking Processes in Hippocampus Tissue after Hypoxic Stress
Roos Van Elzen, Bart Ghesquière, Evy Timmerman, Stefaan Vandamme, Luc Moens, Kris Gevaert and Sylvia Dewilde
DOI: 10.1021/pr900517m
Profiling Protein Markers Associated with Lymph Node Metastasis in Prostate Cancer by DIGE-based Proteomics Analysis
Jun Pang, Wei-Peng Liu, Xiao-Peng Liu, Liao-Yuan Li, You-Qiang Fang, Qi-Peng Sun, Shao-Jun Liu, Ming-Tao Li, Zu-Lan Su and Xin Gao
DOI: 10.1021/pr900953s
Tandem 18O Stable Isotope Labeling for Quantification of N-Glycoproteome
Ze Liu, Jing Cao, Yifeng He, Liang Qiao, Congjian Xu, Haojie Lu and Pengyuan Yang
DOI: 10.1021/pr900528j
Differential Proteomic Profiling Identifies Novel Molecular Targets of Paclitaxel and Phytoagent Deoxyelephantopin against Mammary Adenocarcinoma Cells
Wai-Leng Lee, Tuan-Nan Wen, Jeng-Yuan Shiau and Lie-Fen Shyur
DOI: 10.1021/pr900543e
Functional Divergence of Helicobacter pylori Related to Early Gastric Cancer
Kuvat T. Momynaliev, Sergey V. Kashin, Vera V. Chelysheva, Oksana V. Selezneva, Irina A. Demina, Marya V. Serebryakova, Dmitry Alexeev, Vladimir A. Ivanisenko, Ewgeniya Aman and Vadim M. Govorun
DOI: 10.1021/pr900586w
Proteomic Analyses of the Developing Chicken Cardiovascular System
Els Bon, Regine Steegers, Eric A. P. Steegers, Nicolette Ursem, Halima Charif, Peter C. Burgers, Theo M. Luider and Lennard J. M. Dekker
DOI: 10.1021/pr900614w
Phosphoproteomic Analysis Reveals the Multiple Roles of Phosphorylation in Pathogenic Bacterium Streptococcus pneumoniae
Xuesong Sun, Feng Ge, Chuan-Le Xiao, Xing-Feng Yin, Ruiguang Ge, Liu-Hui Zhang and Qing-Yu He
DOI: 10.1021/pr900612v
Temporal Proteomics Profiling of Lipid Rafts in CCR6-Activated T Cells Reveals the Integration of Actin Cytoskeleton Dynamics
Shu-Ling Lin, Chih-Wei Chien, Chia-Li Han, Eric S.-W. Chen, Shao-Hsuan Kao, Yu-Ju Chen and Fang Liao
DOI: 10.1021/pr9006156
Ambient pH Stress Inhibits Spore Germination of Penicillium expansum by Impairing Protein Synthesis and Folding: A Proteomic-Based Study
Boqiang Li, Tongfei Lai, Guozheng Qin and Shiping Tian
DOI: 10.1021/pr900622j
Simple Method for Quantitative Analysis of N-Linked Glycoproteins in Hepatocellular Carcinoma Specimens
Hyoung-Joo Lee, Keun Na, Eun-Young Choi, Kyung Sik Kim, Hoguen Kim and Young-Ki Paik
DOI: 10.1021/pr900649b
Metabolic Profiling of Human Lung Cancer Tissue by 1H High Resolution Magic Angle Spinning (HRMAS) NMR Spectroscopy
Cáludia M. Rocha, António S. Barros, Ana M. Gil, Brian J. Goodfellow, Eberhard Humpfer, Manfred Spraul, Isabel M. Carreira, Joana B. Melo, João Bernardo, Ana Gomes, Vitor Sousa, Lina Carvalho and Iola F. Duarte
DOI: 10.1021/pr9006574
Development of High-Throughput Chemical Extraction Techniques and Quantitative HPLC-MS/MS (SRM) Assays for Clinically Relevant Plasma Proteins
Chris Barton, Richard G. Kay, Wolfgang Gentzer, Frank Vitzthum and Steve Pleasance
DOI: 10.1021/pr900658d
Worms from Venus and Mars: Proteomics Profiling of Sexual Differences in Caenorhabditis elegans Using in Vivo 15N Isotope Labeling
Bastiaan B. J. Tops, Sharon Gauci, Albert J. R. Heck and Jeroen Krijgsveld
DOI: 10.1021/pr900678j
Quantitative Plasma Proteomic Profiling Identifies the Vitamin E Binding Protein Afamin as a Potential Pathogenic Factor in SIV Induced CNS Disease
Gurudutt Pendyala, Sunia A. Trauger, Gary Siuzdak and Howard S. Fox
DOI: 10.1021/pr900685u
Post-Translational Modifications to Toxoplasma gondii α- and β-Tubulins Include Novel C-Terminal Methylation
Hui Xiao, Kamal El Bissati, Pascal Verdier-Pinard, Berta Burd, Hongshan Zhang, Kami Kim, Andras Fiser, Ruth Hogue Angeletti and Louis M. Weiss
DOI: 10.1021/pr900699a
Global Genomic and Proteomic Analysis Identifies Biological Pathways Related to High-Risk Neuroblastoma
Qing-Rong Chen, Young K. Song, Li-Rong Yu, Jun S. Wei, Joon-Yong Chung, Stephen M. Hewitt, Timothy D. Veenstra and Javed Khan
DOI: 10.1021/pr900701v
Detecting Changes in the Thiol Redox State of Proteins Following a Decrease in Oxygen Concentration Using a Dual Labeling Technique
James K. C. Lui, Richard Lipscombe and Peter G. Arthur
DOI: 10.1021/pr900702z
MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics
Peter Mortensen, Joost W. Gouw, Jesper V. Olsen, Shao-En Ong, Kristoffer T. G. Rigbolt, Jakob Bunkenborg, Jürgen Cox, Leonard J. Foster, Albert J. R. Heck, Blagoy Blagoev, Jens S. Andersen and Matthias Mann
DOI: 10.1021/pr900721e
Probing the Metabolic Aberrations Underlying Mutant Huntingtin Toxicity in Yeast and Assessing Their Degree of Preservation in Humans and Mice
P. Matthew Joyner, Ronni M. Matheke, Lindsey M. Smith and Robert H. Cichewicz
DOI: 10.1021/pr900734g
Effect of the Histone Deacetylase Inhibitor Trichostatin A on the Metabolome of Cultured Primary Hepatocytes
James K. Ellis, Pui Hei Chan, Tatyana Doktorova, Toby J. Athersuch, Rachel Cavill, Tamara Vanhaecke, Vera Rogiers, Mathieu Vinken, Jeremy K. Nicholson, Timothy M. D. Ebbels and Hector C. Keun
DOI: 10.1021/pr9007656
Ceramide Kinase Profiling by Mass Spectrometry Reveals a Conserved Phosphorylation Pattern Downstream of the Catalytic Site
Wei-Qiang Chen, Christine Graf, David Zimmel, Philipp Rovina, Kurt Krapfenbauer, Markus Jaritz, Peter J. Parker, Gert Lubec and Frédéric Bornancin
DOI: 10.1021/pr900763z
Quantitative Phosphoproteomic Analysis of the STAT3/IL-6/HIF1α Signaling Network: An Initial Study in GSC11 Glioblastoma Stem Cells
Carol L. Nilsson, Roslyn Dillon, Arugadoss Devakumar, Stone D.-H. Shi, Michael Greig, John C. Rogers, Bryan Krastins, Michael Rosenblatt, Gregory Kilmer, Michael Major, Barbara J. Kaboord, David Sarracino, Taha Rezai, Amol Prakash, Mary Lopez, Yongjie Ji, Waldemar Priebe, Frederick F. Lang, Howard Colman and Charles A. Conrad
DOI: 10.1021/pr9007927
Acetone Precipitation of Proteins and the Modification of Peptides
Deborah M. Simpson and Robert J. Beynon
DOI: 10.1021/pr900806x
Proteomic Identification of Overexpressed PRDX 1 and Its Clinical Implications in Ovarian Carcinoma
Kwang-hoe Chung, Dong Hyeon Lee, Youkyong Kim, Tae-heon Kim, Jin Hyong Huh, Sang-geun Chung, Sunyoung Lee, Chan Lee, Jung Jae Ko and Hee Jung An
DOI: 10.1021/pr900811x
Hyperglycemia Alters the Schwann Cell Mitochondrial Proteome and Decreases Coupled Respiration in the Absence of Superoxide Production
Liang Zhang, Cuijuan Yu, Francisco E. Vasquez, Nadya Galeva, Isaac Onyango, Russell H. Swerdlow and Rick T. Dobrowsky
DOI: 10.1021/pr900818g
Phenotyping of an in Vitro Model of Ischemic Penumbra by iTRAQ-Based Shotgun Quantitative Proteomics
Arnab Datta, Jung Eun Park, Xin Li, Huoming Zhang, Zhi Shan Ho, Klaus Heese, Sai Kiang Lim, James P. Tam and Siu Kwan Sze
DOI: 10.1021/pr900829h
Comparative Protein Profiling Reveals Minichromosome Maintenance (MCM) Proteins As Novel Potential Tumor Markers for Meningiomas
Okay Saydam, Ozlem Senol, Tieneke B. M. Schaaij-Visser, Thang V. Pham, Sander R. Piersma, Anat O. Stemmer-Rachamimov, Thomas Wurdinger, Saskia M. Peerdeman and Connie R. Jimenez
DOI: 10.1021/pr900834h
Quantitative Organelle Proteomics of MCF-7 Breast Cancer Cells Reveals Multiple Subcellular Locations for Proteins in Cellular Functional Processes
Amal T. Qattan, Claire Mulvey, Mark Crawford, Darren A. Natale and Jasminka Godovac-Zimmermann
DOI: 10.1021/pr9008332
Proteomic Analysis of the Murine Liver in Response to a Combined Exposure to Psychological Stress and 7,12-Dimethylbenz(a)anthracene
Melanie S. Flint, Brian L. Hood, Mai Sun, Nicolas A. Stewart, Jacqueline Jones-Laughner and Thomas P. Conrads
DOI: 10.1021/pr900861j
Expression Profiling of Fibroblasts Identifies Cell Cycle Abnormalities in Schizophrenia
L. Wang, H. E. Lockstone, P. C. Guest, Y. Levin, A. Palotás, S. Pietsch, E. Schwarz, H. Rahmoune, L. W. Harris, D. Ma and S. Bahn
DOI: 10.1021/pr900867x
Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America
Juan J. Calvete, Libia Sanz, Pedro Cid, Pilar de la Torre, Marietta Flores-Díaz, M. Cristina Dos Santos, Adolfo Borges, Adolfo Bremo, Yamileth Angulo, Bruno Lomonte, Alberto Alape-Girón and José María Gutiérrez
DOI: 10.1021/pr9008749
Identification of Serum Biomarkers for Colorectal Cancer Metastasis Using a Differential Secretome Approach
Hua Xue, Bingjian Lü, Jun Zhang, Minliang Wu, Qiong Huang, Qiang Wu, Hongqiang Sheng, Dongdong Wu, Jianwen Hu and Maode Lai
DOI: 10.1021/pr9008817
The SMN Interactome Includes Myb-Binding Protein 1a
Heidi R. Fuller, Nguyen Thi Man, Le Thanh Lam, Le Thiet Thanh, Rebecca A. Keough, Arndt Asperger, Thomas J. Gonda and Glenn E. Morris
DOI: 10.1021/pr900884g
Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches
José María Gutiérrez, Libia Sanz, Marietta Flores-Díaz, Lucía Figueroa, Marvin Madrigal, María Herrera, Mauren Villalta, Guillermo León, Ricardo Estrada, Adolfo Borges, Alberto Alape-Girón and Juan J. Calvete
DOI: 10.1021/pr9009518
Technical Notes
The Effects of Rosiglitazone and High Glucose on Protein Expression in Endothelial Cells
Renato Millioni, Lucia Puricelli, Elisabetta Iori, Giorgio Arrigoni and Paolo Tessari
DOI: 10.1021/pr900435z
MS/MS/MS Reveals False Positive Identification of Histone Serine Methylation
Junmei Zhang, Yue Chen, Zhihong Zhang, Gang Xing, Joanna Wysocka and Yingming Zhao
DOI: 10.1021/pr900864s
Evaluating the Performance of New Approaches to Spot Quantification and Differential Expression in 2-Dimensional Gel Electrophoresis Studies
Jeffrey S. Morris, Brittan N. Clark, Wei Wei and Howard B. Gutstein
DOI: 10.1021/pr9005603
Artificial Decoy Spectral Libraries for False Discovery Rate Estimation in Spectral Library Searching in Proteomics
Henry Lam, Eric W. Deutsch and Ruedi Aebersold
DOI: 10.1021/pr900947u
Identification of Neisseria meningitidis Outer Membrane Vesicle Complexes Using 2-D High Resolution Clear Native/SDS-PAGE
Juan Marzoa, Sandra Sánchez, Carlos M. Ferreirós and María Teresa Criado
DOI: 10.1021/pr9006409
MRMaid-DB: A Repository of Published SRM Transitions
Jennifer A. Cham (Mead), Luca Bianco, Chris Barton and Conrad Bessant
DOI: 10.1021/pr900713u
New Algorithm for the Identification of Intact Disulfide Linkages Based on Fragmentation Characteristics in Tandem Mass Spectra
Seonhwa Choi, Jaeho Jeong, Seungjin Na, Hyo Sun Lee, Hwa-Young Kim, Kong-Joo Lee and Eunok Paek
DOI: 10.1021/pr900771r
The Journal of Proteome Research provides content encompassing all aspects of global protein analysis and function, emphasizing the synergy between physical and life sciences resulting in a multidisciplinary approach to the understanding of biological processes.
In 2008 the Journal of Proteome Research recorded an ISI Impact Factor of 5.684 and 39% growth in total citations to 8,043 as reported in the 2008 Journal Citations Reports® by Thomson Reuters.
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