单一顺序 Unique sequence

互联网2013-11-14

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单一顺序又称非重复顺序，是指在基因组中只有 1 个或几个拷贝，真核中占 40-70% 。真核基因组中大多数基因是单拷贝的，如卵清蛋白，丝心蛋白等基因。但单一顺序在真核生物中大部分不编码，编码的顺序仅占百分之几。原核生物除了短片段的回文顺序（反向重复）和 18S ， 28S ， 5SrRNA 和 tRNA 基因以外皆为单一顺序，这些单一顺序基本上都编码。真核生物中单一顺序编码的基因在表达时常有两步放大作用。如蚕的丝心蛋白基因只有一个拷贝但可转录产生 10⁴ mRNA ，而每个 mRNA 又可反复使用产生 10⁵ 个丝心蛋白分子。而重复顺序编码的基因就没有第二步放大作用。

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