Quantitation of Heme Oxygenase (HO-1) Copies in Human Tissues by Competitive RT/PCR
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A variety of oxidative stress-inducing agents, such as metals, ultra-violet (UV) light, heme, and hemoglobin have been implicated in the pathogenesis of the inflammatory process. The cellular response to such agents involves the production of a number of soluble mediators including acute phase proteins, eicosanoids, and various cytokines.