大鼠及小鼠麻醉剂量参考

药 物

剂量

途径

麻醉前给药

Atropine

0.002-0.005 mg/100 g BW

0.12 mg/100 g BW

IM, IV, SC

IP

镇静剂

Acepromazine

Diazepam

Ketamine

0.075 mg/100 g BW

0.5 mg/100 g BW

2.0 mg/100 g BW

IM

IP

IM

注射麻醉剂

Ketamine

Pentobarbital

Thiopental

Thiamylal

2.2-4.4 mg/100 g BW

10 mg/100 g BW

2.5 mg/100 g BW

1.5 mg/100 g BW

6.0 mg/100 g BW

2.5 mg/100 g BW

5.0 mg/100 g BW

2.5-5.0 mg/100 g BW

IM

IP

IV

IV

IP

IV

IP

IV

混合注射麻醉剂

Ketamine & Xylazine

Fentanyl& Droperidol & Diazepam

Ketamine & Acepromazine

8.7 & 1.3 mg/100 g BW

0.2-0.5 ml/100g BW (10% solution)

0.5 mg/100g BW

2.2-4.4 & 0.075 mg/100 g BW

IM

IM

IP

IM

吸入麻醉剂

Methoxyflurane

Halothane

CO ₂

Induction: 2-4%

Maintenance: 0.5-1.5%

Induction: 1-3%

Maintenance: 0.5-1.5%

Induction: 10-15 seconds

止痛剂

Meperidine

Pentacozine

Nalbuphine

Butorphanol

Buprenorphine

2.0 mg/100 g BW

0.4 mg/100 g BW

1.0 mg/100 g BW

0.5 mg/100 g BW

0.1-0.5 mg/100 g BW

0.2 mg/100 g BW /12h

0.2 mg/100 g BW /6-8h

IM, SC

IP

IM, SC, IV

IM, SC

IM, SC

SC

IP

不推荐使用的药物

Chloroform

Carbon tetrachloride Chlorpromazine

Ether

Trichloroethylene

Tribromoethanol

药 物

剂量

途径

麻醉前给药

Atropine

0.002-0.005 mg/100 g BW

IM, IV, SC

镇静剂

Acepromazine

Diazepam

Xylazine

Ketamine

0.5 mg/100 g BW

0.25 mg/100 g BW

1.3 mg/100 g BW

2.2 mg/100 g BW

2.0 mg/100 g BW

IM, SC

IP

IM

IM

IP

注射麻醉剂

Fentanyl & Droperidol

Ketamine

Pentobarbital

0.2-0.4 ml/kg (10% solution)

4.4 mg/100 g BW

4-16 mg/100 g BW

5 mg/100 g BW

3-4 mg/100 g BW

3-5 mg/100 g BW

IP

IM

IP

IV

IV

IP

混合注射麻醉剂

Ketamine & Xylazine

Ketamine & Acepromazine

Ketamine & Pentobarbital

Innovar-Vet & Pentobarbital

Inactin

Acepromazine & Pentobarbital

8.7 & 1.3 mg/100 g BW

2-4 & 0.075 mg/100 g BW

4.4 & 2.5 mg/100 g BW

6.0 & 2.1 mg/100 g BW

(I)0.13-0.3 ml/kg (10% solution) & (P)1-2 mg/100 g BW

100 mg/kg

0.5 & 2.5-3 mg/100 g BW

IM

IM

(K)IM, (P)IP

(K)IM, (P)IV

(I)IM, (P)IP

IP

(A)IM, SC, (P)IP

吸入麻醉剂

Methoxyflurane

Halothane

Enflurane

Ether

Induction: 2-4%

Maintenance: 0.5-1.5%

Induction: 1-3%

Maintenance: 0.5-1.5%

Induction: 3-4%

Maintenance: 1-3%

棉花上沾1-2ml放到chamber中作用

止痛剂

Meperidine

Pentacozine

Butorphanol

Nalbuphine

Buprenorphine

0.3-0.5 mg/100 g BW

0.2 mg/100 g BW

0.05-2 ml/kg

0.1-0.2 mg/100 g BW

0.01-0.05 mg/100g every 12 hr

IM, IV,IP

IM, IV, SC

IM, SC

IM, SC

SC

不推荐使用的药物

Chlorpromazine

Chloral hydrate

Chloroform

Tribromoethanol

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