LC-MS/MS Screen for Xenobiotics and Metabolites
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Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is now considered as a perfect complement to HPLC-DAD (diode array detection) and gas chromatography (GC)-MS for the general unknown screening of drugs and toxic compounds.
Here we describe a procedure applied routinely in our laboratory for clinical and forensic applications using the QTRAP™ technology.