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Less common disorders:I

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DISEASE AND CAUSES PATHOPHYSIOLOGY SIGNS AND SYMPTOMS
Idiopathic pulmonary fibrosis  
  • Chronic progressive lung disease associated with inflammation and fibrosis.
  • Cause unknown
Interstitial inflammation consists of an alveolar septal infiltrate of lymphocytes, plasma cells, and histiocytes. Fibrotic areas are composed of dense acellular collagen. Areas of honeycombing that form are composed of cystic fibrotic air spaces, frequently lined with bronchiolar epithelium and filled with mucus. Smooth muscle hyperplasia may occur in areas of fibrosis and honeycombing.
  • Dyspnea
  • Nonproductive cough
  • Chest heaviness
  • Wheezing
  • Anorexia
  • Weight loss
Irritable bowel syndrome  
  • Disordered motor and sensory function of GI tract with unknown cause, although environmental, infectious, genetic, autoimmune, and host factors are suspected
Altered neural stimulation results in nonpropulsive segmentation waves, leading to constipation.
  • Abdominal pain relieved with defecation
  • Altered stool frequency
  • Altered stool form
  • Altered stool passage
  • Passage of mucus
  • Bloating and abdominal distention

 

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