Single Cell PCR: Theory, Practice, and Clinical Applications
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The analysis of genetic material is fundamental to many medical and scientific applications. These include diagnosis of genetic disorders from preimplantation embryos (1 ) prenatal diagnosis (amniocentesis and chorionic villus sampling [CVS]), forensic analysis (2 ) analysis of pathological specimens (3 ) paternity testing (4 ) disease screening, (e.g., antenatal cystic fibrosis screening (5 ) disease diagnosis, gene therapy (6 ) formation and analysis of transgeinc animals (7 ) and investigation of oncogenes (8 ). However, the major reason for the analysis of genetic material, particularly in medicine, is the diagnosis of genetic disorders