HLA-DPA1 and -DPB1 Typing Using the PCR and Nonradioactive Sequence-Specific Oligonucleotide Probes
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The class II molecules of the human major histocompatibility complex are cell surface glycoproteins encoded by a series of genes located on the short arm of chromosome 6 in the HLA-D region. These molecules consist of an α and � chain that associate as heterodimers on the surface of antigen presenting cells. They serve as receptors for processed peptides derived primarily from mem-brane and extracellular proteins that they present to CD4+ lymphocytes.
![PSMB9 LMP2=proteasome LMP2.s {alternatively spliced} [human, EBV-transformed B lymphoblastoid typing cell lines, mRNA, 645 nt].](https://img1.dxycdn.com/p/s14/2024/0514/752/2760093895118520971.jpg!wh200)
